The optimization logic takes into consideration:
- Transportation – There may be as many as twenty different transportation options to and from the cell processing facility. The system chooses the best option considering a variety of risk factors inherent in each route, scheduled patient appointment times, and available capacity at the cell processing facility.
- Manufacturing constraints – Treatments must be scheduled into the cell processing facility while respecting resource capacities, batch step durations, and precedence constraints.
- Operating calendars and statuses – The various process participants and resources have their own operating calendars and statuses that must be respected. For example, the system must respect the operating hours of physician's offices and it must respect the status of transportation routes, not choosing routes that are disabled for use.
- Inbound and outbound expiration constraints – The system must respect inbound and outbound expiration constraints, scheduling all activities that occur between the start and end of expiration, including transportation, to occur within the expiration limit.
- Regulatory requirements – Since there are regulatory minimum and maximum times between treatments, all treatments for a regimen must be scheduled at one time to ensure that these constraints are respected.
Cancer Treatment Scheduling Page 4 of 5